ACLY Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-957	100 μg

Catalog No. 89-118-957 Supplier Abnova Corporation Supplier No. PAB17293

Description

Rabbit polyclonal antibody raised against synthetic peptide of ACLY.

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Specifications

• Antigen: ACLY
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ACLY.
• Dilution: Western Blot (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene: ACLY
• Gene Accession No.: P53396
• Gene Alias: ACL/ATPCL/CLATP
• Gene Symbols: ACLY
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to residues surrounding serine 363 of human ACLY.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 47
• Test Specificity: This antibody detects endogenous levels of total ACLY protein.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only