ACLY Rabbit anti-Human, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against recombinant ACLY.
Manufacturer: Abnova Corporation PAB21446
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeqSequence: CANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITE
|Immunohistochemistry (1:20-1:50) Western Blot (1:250-1:500) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to amino acids of human ACLY.|
|Antigen affinity purification|
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Rabbit polyclonal antibody raised against recombinant ACLY.|
|In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
For Research Use Only