ACO1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ACO1.

Supplier:  Abnova Corporation PAB18048

Catalog No. 89-119-624

Description

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq]

Specifications

• Antigen: ACO1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ACO1.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P21399
• Gene Symbols: ACO1
• Immunogen: A synthetic peptide corresponding to human ACO1.
• Regulatory Status: RUO
• Gene ID (Entrez): 48
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50∼1:100) IELISA (1:20000) The optimal working dilution should be determined by the end user.
• Gene: ACO1
• Gene Alias: ACONS/IREB1/IREBP/IREBP1/IRP1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to ACO1.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only