ACTL7A, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-090	100 μg

Catalog No. 89-120-090 Supplier Abnova Corporation Supplier No. PAB18530

Description

Rabbit polyclonal antibody raised against partial recombinant ACTL7A.

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. [provided by RefSeq

Specifications

• Antigen: ACTL7A
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against partial recombinant ACTL7A.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:100-1:500) ELISA (1:20000-1:80000) The optimal working dilution should be determined by the end user.
• Formulation: In buffer containing 0.02% sodium azide
• Gene: ACTL7A
• Gene Accession No.: BC014610
• Gene Symbols: ACTL7A
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to amino acids 42-283 of human ACTL7A.
• Purification Method: Protein A purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10881
• Test Specificity: This antibody is specific to ACTL7A.
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only