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Description
This gene encodes a 42.3kDa subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kDa. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq
Specifications
Specifications
| Antigen | ACTR1B |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ACTR1B. |
| Dilution | ELISA (1:160000) Western Blot (1:1000-2000) The optimal working dilution should be determined by the end user. |
| Formulation | In serum (0.02% sodium azide) |
| Gene | ACTR1B |
| Gene Accession No. | P42025 |
| Gene Alias | ARP1B/CTRN2/PC3 |
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