ADAMTS4 Rabbit anti-Dog, Horse, Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS4.

Supplier:  Abnova Corporation PAB16220

Catalog No. 89-118-108

Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq

Specifications

• Antigen: ADAMTS4
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS4.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: O75173
• Gene Symbols: ADAMTS4
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human ADAMTS4.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: C-terminal domain of human .
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ADAMTS4
• Gene Alias: ADAMTS-2/ADAMTS-4/ADMP-1/KIAA0688
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 9507
• Target Species: Canine, Equine, Human
• Form: Liquid

For Research Use Only