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ADAMTS4 Rabbit anti-Dog, Horse, Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89118107 Shop All Abnova Corporation Products
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89-118-107 50 μg
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Catalog No. 89-118-107 Supplier Abnova Corporation Supplier No. PAB16218
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS4.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq

Specifications

Antigen ADAMTS4
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS4.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.6 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene ADAMTS4
Gene Accession No. O75173
Gene Alias ADAMTS-2/ADAMTS-4/ADMP-1/KIAA0688
Gene Symbols ADAMTS4
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human ADAMTS4.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9507
Test Specificity internal domain of human .
Target Species Canine, Equine, Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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