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Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq
Specifications
Specifications
| Antigen | ADAMTS8 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS8. |
| Dilution | ELISA (1:80000) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In buffer containing 0.02% sodium azide |
| Gene | ADAMTS8 |
| Gene Accession No. | Q9UP79 |
| Gene Alias | ADAM-TS8/FLJ41712/METH2 |
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