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Description
Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq]
Specifications
Specifications
| Antigen | ADM |
| Applications | ELISA, Immunoprecipitation |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ADM. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal) |
| Gene | ADM |
| Gene Alias | AM |
| Gene Symbols | ADM |
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