ADRA1B Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.
Manufacturer: Abnova Corporation PAB16419
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20kb that interrupts the coding region. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.|
|In PBS (0.09% sodium azide)|
|A synthetic peptide (conjugated with KLH) corresponding to human ADRA1B.|
|C-terminal Cytoplasmic domain of human.|
|Immunohistochemistry (PFA fixed)|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.|
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