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ADRA1B Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89127134 Shop All Abnova Corporation Products
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50 μg
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89-127-134 50 μg
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Catalog No. 89-127-134 Supplier Abnova Corporation Supplier No. PAB25520
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20kb that interrupts the coding region. [provided by RefSeq

Specifications

Antigen ADRA1B
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (6 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene ADRA1B
Gene Alias ADRA1/ALPHA1BAR
Gene Symbols ADRA1B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids at 1st cytoplasmic domain of human ADRA1B.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50%).
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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