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ADRA2C Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89127149 Shop All Abnova Corporation Products
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89-127-149 50 μg
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Catalog No. 89-127-149 Supplier Abnova Corporation Supplier No. PAB25535
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ADRA2C.

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq

Specifications

Antigen ADRA2C
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ADRA2C.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (26 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene ADRA2C
Gene Alias ADRA2L2/ADRA2RL2/ADRARL2/ALPHA2CAR
Gene Symbols ADRA2C
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 18 amino acids at N-terminal extracellular domain of human ADRA2C.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 152
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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