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AGT Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89129278 Shop All Abnova Corporation Products
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89-129-278 50 μg
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Catalog No. 89-129-278 Supplier Abnova Corporation Supplier No. PAB27760
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Description

Rabbit polyclonal antibody raised against synthetic peptide of AGT.

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq

Specifications

Antigen AGT
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of AGT.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene AGT
Gene Accession No. P01019
Gene Alias ANHU/FLJ92595/FLJ97926/SERPINA8
Gene Symbols AGT
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 12 amino acid at internal region of human AGT.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 183
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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