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AKAP13, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89126642 Shop All Abnova Corporation Products
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89-126-642 100 μL
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Catalog No. 89-126-642 Supplier Abnova Corporation Supplier No. PAB24967
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Description

Rabbit polyclonal antibody raised against synthetic peptide of AKAP13.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in at least 3 transcript variants encoding different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway and, in addition, function as protein kinase A-anchoring proteins. [provided by RefSeq

Specifications

Antigen AKAP13
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of AKAP13.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene AKAP13
Gene Alias AKAP-Lbc/ARHGEF13/BRX/FLJ11952/FLJ43341/HA-3/Ht31/LBC/PROTO-LB/PROTO-LBC/c-lbc
Gene Symbols AKAP13
Host Species Rabbit
Immunogen A synthetic peptide corresponding to AKAP13.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11214
Test Specificity AKAP13 polyclonal antibody detects endogenous levels of AKAP13 protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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