ALDH2, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ALDH2.

Supplier:  Abnova Corporation PAB3078

Catalog No. 89-130-816

Description

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq

Specifications

• Antigen: ALDH2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ALDH2.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_000681;P05091
• Gene Symbols: ALDH2
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human ALDH2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
• Gene: ALDH2
• Gene Alias: ALDH-E2/ALDHI/ALDM/MGC1806
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 217
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only