ALDH2, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-816	400 μL

Catalog No. 89-130-816 Supplier Abnova Corporation Supplier No. PAB3078

Description

Rabbit polyclonal antibody raised against synthetic peptide of ALDH2.

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq

Specifications

• Antigen: ALDH2
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ALDH2.
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: ALDH2
• Gene Accession No.: NP_000681;P05091
• Gene Alias: ALDH-E2/ALDHI/ALDM/MGC1806
• Gene Symbols: ALDH2
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human ALDH2.
• Purification Method: Protein A purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 217
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only