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Description
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq
Specifications
Specifications
| Antigen | ALDH6A1 |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ALDH6A1. |
| Dilution | Western Blot (1:1000) Immunohistochemistry (1:10-50) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | ALDH6A1 |
| Gene Accession No. | NP_005580;Q02252 |
| Gene Alias | MGC40271/MMSADHA/MMSDH |
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