ALOX5 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-862	100 μL

Catalog No. 89-115-862 Supplier Abnova Corporation Supplier No. PAB12488

Description

Rabbit polyclonal antibody raised against synthetic peptide of ALOX5.

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq

Specifications

• Antigen: ALOX5
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ALOX5.
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (30% glycerol, 0.09% sodium azide)
• Gene: ALOX5
• Gene Accession No.: P09917
• Gene Alias: 5-LO/5-LOX/5LPG/LOG5/MGC163204
• Gene Symbols: ALOX5
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 100-200 of human ALOX5.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 240
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only