MilliporeSigma™ Rabbit anti-AMACR, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABC925

Catalog No. ABC925MI

Description

Specifically detects AMACR in Human samples, and it is validated for Immunohistochemistry, Western Blotting

Alpha-methylacyl-CoA racemase is encoded by the AMACR gene and catalyzes the convertion of various (2R)-methylacyl-CoA esters to the corresponding (2S)-methylacyl-CoA epimers. AMACR deficiency (AMACRD) is a rare autosomal recessive peroxisomal disorder characterized by elevated plasma concentrations of pristanic acid C27-bile-acid intermediates, resulting in variable neurodegenerative symptoms affecting the central and peripheral nervous systems, including seizures, visual failure, sensorimotor neuropathy, spasticity, migraine, and white matter hyperintensities on brain imaging.

Specifications

• Antigen: AMACR
• Classification: Polyclonal
• Gene Accession No.: Q9UHK6
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Immunohistochemistry, Western Blot
• Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: AMACR
• Immunogen: GST-tagged recombinant protein corresponding to human AMACR near the N-terminal.
• Quantity: 100 μg
• Research Discipline: Apoptosis, Cancer
• Gene ID (Entrez): NP_055139
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only