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ANAPC5, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89120765 Shop All Abnova Corporation Products
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100 μg
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89-120-765 100 μg
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Catalog No. 89-120-765 Supplier Abnova Corporation Supplier No. PAB19235
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Description

Rabbit polyclonal antibody rasied against synthetic peptide of ANAPC5.

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq

Specifications

Antigen ANAPC5
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody rasied against synthetic peptide of ANAPC5.
Dilution Western Blot (1-2 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene ANAPC5
Gene Accession No. Q9UJX4
Gene Alias APC5
Gene Symbols ANAPC5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 17 amino acids near internal region of human ANAPC5.
Purification Method Peptide affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51433
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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