ANTXR1 (phospho Y382), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-607	400 μL

Catalog No. 89-133-607 Supplier Abnova Corporation Supplier No. PAB8155

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ANTXR1.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq

Specifications

• Antigen: ANTXR1
• Applications: Dot Blot, ELISA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ANTXR1.
• Dilution: ELISA (1:1000) Dot Blot (1:500) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: ANTXR1
• Gene Accession No.: NP_115584;Q9H6X2
• Gene Alias: ATR/FLJ10601/FLJ11298/FLJ21776/TEM8
• Gene Symbols: ANTXR1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y382 of human ANTXR1.
• Purification Method: Protein A purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 84168
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only