ANTXR1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ANTXR1.

Supplier:  Abnova Corporation PAB13109

Catalog No. 89-116-361

Description

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq

Specifications

• Antigen: ANTXR1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ANTXR1.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: NP_444262
• Gene Symbols: ANTXR1
• Immunogen: A synthetic peptide corresponding to internal region 13 amino acids of human ANTXR1.
• Regulatory Status: RUO
• Gene ID (Entrez): 84168
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ANTXR1
• Gene Alias: ATR/FLJ10601/FLJ11298/FLJ21776/TEM8
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: It is human, mouse, and rat reactive. It will recognize all three isoforms.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only