Learn More
Description
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist. [provided by RefSeq
Specifications
Specifications
| Antigen | AP1B1 |
| Applications | Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of AP1B1. |
| Dilution | Immunohistochemistry (1:1000-1:5000) Western Blot (1:100-1:10000) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from PBS |
| Gene | AP1B1 |
| Gene Accession No. | Q10567;O35643;P52303;Q2KJB2 |
| Gene Alias | ADTB1/AP105A/BAM22/CLAPB2 |
| Show More |
For Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.