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APAF1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of APAF1.

Manufacturer:  Abnova Corporation PAB18086

Catalog No. 89-119-661


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Description

Description

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Specifications

APAF1
Unconjugated
Western Blot (1:500~1:1000) Immunohistochemistry (1:50~1:100) ELISA(1:10000) The optimal working dilution should be determined by the end user.
APAF1
Liquid
APAF1
A synthetic peptide corresponding to human APAF1.
RUO
Primary
317
Human
ELISA, Immunohistochemistry, Immunohistochemistry (PFA fixed), Western Blot
Rabbit polyclonal antibody raised against synthetic peptide of APAF1.
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
O14727
CED4|DKFZp781B1145
Rabbit
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
This antibody is specific to APAF1.
SDS
Documents
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