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APAF1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89134397 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-134-397 100 μg
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Catalog No. 89-134-397 Supplier Abnova Corporation Supplier No. PAB9764

Description

Rabbit polyclonal antibody raised against synthetic peptide of APAF1.

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Antigen APAF1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description apoptotic peptidase activating factor 1
Formulation In PBS (0.02% sodium azide)
Gene APAF1
Gene Alias CED4, DKFZp781B1145
Gene Symbols APAF1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids 1158-1177 of Human APAF1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 317
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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