APEX1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against recombinant APEX1.

Supplier:  Abnova Corporation PAB12487

Catalog No. 89-115-861

Description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]

Specifications

• Antigen: APEX1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against recombinant APEX1.
• Formulation: In Tris-glycine, 150mM NaCl (0.05% sodium azide)
• Gene Accession No.: P27695
• Gene Symbols: APEX1
• Immunogen: Recombinant protein corresponding to human APEX1.
• Regulatory Status: RUO
• Gene ID (Entrez): 328
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Dilution: Immunocytochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) Immunoprecipitation (7 ug/mL) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: APEX1
• Gene Alias: APE/APE-1/APE1/APEN/APEX/APX/HAP1/REF-1/REF1
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to the human APE/ref-1protein.
• Content And Storage: Store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only