APOB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-847	100 μg

Catalog No. 89-118-847 Supplier Abnova Corporation Supplier No. PAB17099

Description

Rabbit polyclonal antibody raised against recombinant APOB.

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq

Specifications

• Antigen: APOB
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against recombinant APOB.
• Dilution: Western Blot (1:5000-1:20000) ELISA (1:5000-1:20000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.02% sodium azide)
• Gene: APOB
• Gene Alias: FLDB
• Gene Symbols: APOB
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to human APOB.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 338
• Test Specificity: This antibody specifically binds to human APOB.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only