APOE Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-936	100 μg

Catalog No. 89-128-936 Supplier Abnova Corporation Supplier No. PAB27425

Description

Rabbit polyclonal antibody raised against synthetic peptide of APOE.

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

• Antigen: APOE
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of APOE.
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (2.5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: APOE
• Gene Accession No.: NP_000032
• Gene Alias: AD2/LPG/MGC1571/apoprotein
• Gene Symbols: APOE
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 19 amino acids at C-terminus of human APOE.
• Purification Method: Peptide affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 348
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG

For Research Use Only