APOE Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against a recombinant APOE.

Supplier:  Abnova Corporation PAB8547

Catalog No. 89-133-743

Description

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

• Antigen: APOE
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against a recombinant APOE.
• Formulation: In PBS, pH 7.2 (30% glycerol, 0.01% thimerosal)
• Gene Alias: AD2/LPG/MGC1571/apoprotein
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: APOE
• Gene Symbols: APOE
• Immunogen: Recombinant protein corresponding to human APOE.
• Regulatory Status: RUO
• Gene ID (Entrez): 348
• Content And Storage: Store at -20°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only