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Apolipoprotein E3, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89121382 Shop All Abnova Corporation Products
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150 μg
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Catalog No. Quantity
89-121-382 150 μg
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Catalog No. 89-121-382 Supplier Abnova Corporation Supplier No. PAB19855
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Description

Rabbit polyclonal antibody raised against recombinant Apolipoprotein E3.

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

Antigen Apolipoprotein E3
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against recombinant Apolipoprotein E3.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.5 (0.02% sodium azide, 50% glycerol (v/v))
Gene APOE
Gene Alias AD2/LPG/MGC1571/apoprotein
Gene Symbols APOE
Host Species Rabbit
Immunogen Recombinant protein corresponding to human Apolipoprotein E3.
Purification Method Affinity purification
Quantity 150 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 348
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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