APP Rabbit anti-Human, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-348	100 μL

Catalog No. 89-114-348 Supplier Abnova Corporation Supplier No. PAB0696

Description

Rabbit polyclonal antibody raised against synthetic peptide of APP.

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

Sequence: ETHLHWHTVAKET

Specifications

• Antigen: APP
• Applications: Immunohistochemistry
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of APP.
• Dilution: Immunohistochemistry (1:500-1:3000) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from PBS
• Gene: APP
• Gene Accession No.: P05067
• Gene Alias: AAA/ABETA/ABPP/AD1/APPI/CTFgamma/CVAP/PN2
• Gene Symbols: APP
• Host Species: Rabbit
• Immunogen: A mixture of synthetic peptides (conjugated with KLH) corresponding to amino acids 145-157, 388-405, 724-737 of human APP.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 351
• Target Species: Human, Rat
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized

For Research Use Only