AR (phospho S213), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-981	100 μg

Catalog No. 89-126-981 Supplier Abnova Corporation Supplier No. PAB25326

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of AR.

The androgen receptor gene is more than 90kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq

Sequence: E-A-Sp-G-A

Specifications

• Antigen: AR
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of AR.
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: AR
• Gene Accession No.: P10275
• Gene Alias: AIS/DHTR/HUMARA/KD/NR3C4/SBMA/SMAX1/TFM
• Gene Symbols: AR
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S213 of human AR.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 367
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only