ARNT2, Rabbit, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of ARNT2.
Manufacturer: Abnova Corporation PAB17454
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq
|Western Blot (1:500-1:1000) ELISA (1:20000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to internal of human ARNT2.|
|Human, Murine, Rat|
|ELISA, Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of ARNT2.|
|In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody detects endogenous levels of total ARNT2 protein.|
For Research Use Only