ARNT2, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ARNT2.

Manufacturer:  Abnova Corporation PAB17454

Catalog No. 89-119-111

Description

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq

Specifications

• Antigen: ARNT2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ARNT2.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene Accession No.: Q9HBZ2
• Gene Symbols: ARNT2
• Immunogen: A synthetic peptide corresponding to internal of human ARNT2.
• Regulatory Status: RUO
• Gene ID (Entrez): 9915
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) ELISA (1:20000) The optimal working dilution should be determined by the end user.
• Gene: ARNT2
• Gene Alias: KIAA0307/bHLHe1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of total ARNT2 protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only