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ARNT2, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of ARNT2.
Manufacturer: Abnova Corporation PAB17454
Description
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq
Specifications
ARNT2 | |
Polyclonal | |
Rabbit polyclonal antibody raised against synthetic peptide of ARNT2. | |
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol) | |
Q9HBZ2 | |
ARNT2 | |
A synthetic peptide corresponding to internal of human ARNT2. | |
RUO | |
9915 | |
Human, Mouse, Rat | |
Liquid |
ELISA, Western Blot | |
Unconjugated | |
Western Blot (1:500-1:1000) ELISA (1:20000) The optimal working dilution should be determined by the end user. | |
ARNT2 | |
KIAA0307/bHLHe1 | |
Rabbit | |
100 μg | |
Primary | |
This antibody detects endogenous levels of total ARNT2 protein. | |
Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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For Research Use Only