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ARRB1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89119734 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-119-734 100 μg
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Catalog No. 89-119-734 Supplier Abnova Corporation Supplier No. PAB18161
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ARRB1.

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known. [provided by RefSeq

Specifications

Antigen ARRB1
Applications ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ARRB1.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene ARRB1
Gene Accession No. P49407
Gene Alias ARB1/ARR1
Gene Symbols ARRB1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human ARRB1.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 408
Test Specificity This antibody is specific to ARRB1.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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