ATF4 (phospho S245), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-711	100 μL

Catalog No. 89-126-711 Supplier Abnova Corporation Supplier No. PAB25032

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ATF4.

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq

Specifications

• Antigen: ATF4
• Applications: Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ATF4.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunoprecipitation (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene: ATF4
• Gene Alias: CREB-2/CREB2/TAXREB67/TXREB
• Gene Symbols: ATF4
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S245 of ATF4.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 468
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only