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ATF6B Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126566 Shop All Abnova Corporation Products
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89-126-566 100 μL
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Catalog No. 89-126-566 Supplier Abnova Corporation Supplier No. PAB24894
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Rabbit polyclonal antibody raised against synthetic peptide of ATF6B.

The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen ATF6B
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ATF6B.
Dilution Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene ATF6B
Gene Alias CREB-RP/CREBL1/FLJ10066/G13
Gene Symbols ATF6B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to ATF6B.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1388
Test Specificity ATF6B polyclonal antibody detects endogenous levels of ATF6B protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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