ATF6B Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ATF6B.

Supplier:  Abnova Corporation PAB24894

Catalog No. 89-126-566

Description

The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: ATF6B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene: ATF6B
• Gene Symbols: ATF6B
• Immunogen: A synthetic peptide corresponding to ATF6B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: ATF6B polyclonal antibody detects endogenous levels of ATF6B protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ATF6B.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene Alias: CREB-RP/CREBL1/FLJ10066/G13
• Host Species: Rabbit
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1388
• Target Species: Human
• Form: Liquid

For Research Use Only