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Description
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM
Specifications
Specifications
| Antigen | ATG10 |
| Applications | Immunofluorescence, Immunohistochemistry (Frozen) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ATG10. |
| Dilution | Immunohistochemistry (1:100-1:1000) Immunofluorescence (1:100-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from PBS |
| Gene | ATG10 |
| Gene Accession No. | Q9H0Y0 |
| Gene Alias | APG10/APG10L/DKFZp586I0418/FLJ13954/pp12616 |
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