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ATM Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ATM.

Supplier:  Abnova Corporation PAB26713

Catalog No. 89-128-353


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Description

Description

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: E-G-Sp-Q-S
Specifications

Specifications

ATM
Polyclonal
Unconjugated
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
ATM
AT1/ATA/ATC/ATD/ATDC/ATE/DKFZp781A0353/MGC74674/TEL1/TELO1
Rabbit
Affinity chromatography
RUO
472
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Western Blot
1 mg/mL
Rabbit polyclonal antibody raised against synthetic peptide of ATM.
In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Q13315
ATM
A synthetic peptide corresponding to residues surrounding S1981 of human ATM.
100 μg
Primary
Human, Mouse
Liquid
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