ATP6V0A4 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ATP6V0A4.

Supplier:  Abnova Corporation PAB5261

Catalog No. 89-131-789

Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c″, and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq]

Specifications

• Antigen: ATP6V0A4
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ATP6V0A4.
• Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
• Gene Alias: A4/ATP6N1B/ATP6N2/MGC130016/MGC130017/RDRTA2/RTA1C/RTADR/STV1/VPH1/VPP2
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: ATP6V0A4
• Gene Symbols: ATP6V0A4
• Immunogen: A synthetic peptide corresponding to C-terminus of human ATP6V0A4.
• Regulatory Status: RUO
• Gene ID (Entrez): 50617
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only