Aurora Kinase A/B/C, Rabbit, Clone: SP201, Abnova™

Rabbit monoclonal antibody raised against synthetic peptide of human Aurora Kinase A/B/C.

Supplier:  Abnova Corporation MAB12169

Catalog No. 89-110-310

Description

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

• Antigen: Aurora Kinase A/B/C
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Gene: AURKA
• Gene Symbols: AURKA
• Immunogen: A synthetic peptide corresponding to C-terminus region of human Aurora kinase A, B, and C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: 48 kDa (Aurora A), 40 kDa (Aurora B), and 35 kDa (Aurora C).
• Content And Storage: Store at 4°C.
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (PFA fixed)
• Clone: SP201
• Description: Rabbit monoclonal antibody raised against synthetic peptide of human Aurora Kinase A/B/C.
• Formulation: In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
• Gene Alias: AIK/ARK1/AURA/AURORA2/BTAK/MGC34538/STK15/STK6/STK7
• Host Species: Rabbit
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 6790
• Target Species: Human
• Form: Liquid

For Research Use Only