AXIN1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody rasied against synthetic peptide of AXIN1.

Supplier:  Abnova Corporation PAB19323

Catalog No. 89-120-856

Description

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Specifications

• Antigen: AXIN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: AXIN1
• Gene Alias: AXIN/MGC52315
• Host Species: Rabbit
• Purification Method: Peptide affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 8312
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunofluorescence, Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody rasied against synthetic peptide of AXIN1.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: AAC51624
• Gene Symbols: AXIN1
• Immunogen: A synthetic peptide corresponding to 14 amino acids near C-terminus of human AXIN1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only