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BACE1 Rabbit anti-Bovine, Dog, Guinea pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89118358 Shop All Abnova Corporation Products
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89-118-358 50 μg
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Catalog No. 89-118-358 Supplier Abnova Corporation Supplier No. PAB16485
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Description

Rabbit polyclonal antibody raised against synthetic peptide of BACE1.

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

Antigen BACE1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BACE1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene BACE1
Gene Accession No. P56817
Gene Alias ASP2/BACE/FLJ90568/HSPC104/KIAA1149
Gene Symbols BACE1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human BACE1.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23621
Test Specificity Internal domain of human.
Target Species Bovine, Canine, Equine, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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