BACE1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-119-686	100 μg

Catalog No. 89-119-686 Supplier Abnova Corporation Supplier No. PAB18113

Description

Rabbit polyclonal antibody raised against synthetic peptide of BACE1.

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

• Antigen: BACE1
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BACE1.
• Dilution: Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: BACE1
• Gene Accession No.: P56817
• Gene Alias: ASP2/BACE/FLJ90568/HSPC104/KIAA1149
• Gene Symbols: BACE1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to human BACE1.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23621
• Test Specificity: This antibody is specific to BACE1.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only