BACE1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BACE1.

Supplier:  Abnova Corporation PAB18113

Catalog No. 89-119-686

Description

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

• Antigen: BACE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
• Gene: BACE1
• Gene Alias: ASP2/BACE/FLJ90568/HSPC104/KIAA1149
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 23621
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BACE1.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P56817
• Gene Symbols: BACE1
• Immunogen: A synthetic peptide corresponding to human BACE1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to BACE1.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only