BACE2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BACE2.

Supplier:  Abnova Corporation PAB4706

Catalog No. 89-131-530

Description

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

• Antigen: BACE2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BACE2.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: Q9Y5Z0
• Gene Symbols: BACE2
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human BACE2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:100-500) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user.
• Gene: BACE2
• Gene Alias: AEPLC/ALP56/ASP1/ASP21/BAE2/CDA13/CEAP1/DRAP
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 25825
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only