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BAD (phospho S91/S128), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89130713 Shop All Abnova Corporation Products
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89-130-713 100 μL
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Catalog No. 89-130-713 Supplier Abnova Corporation Supplier No. PAB29276
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAD.

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq

Specifications

Antigen BAD
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAD.
Dilution Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene BAD
Gene Accession No. Q92934
Gene Alias BBC2/BCL2L8
Gene Symbols BAD
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S91 of human BAD.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 572
Test Specificity BAD (phospho S91/S128) polyclonal antibody detects endogenous levels of human BAD only when phosphorylated at serine 91/serine 128.
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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