BAD Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BAD.

Manufacturer:  Abnova Corporation PAB18308

Catalog No. 89-119-874

Description

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq

Specifications

• Antigen: BAD
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BAD.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: Q92934
• Gene Alias: BBC2|BCL2L8
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 572
• Target Species: Human, Murine, Rat

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
• Gene: BAD
• Format: Liquid
• Gene Symbols: BAD
• Immunogen: A synthetic peptide corresponding to residues surrounding S134 of human BAD.
• Quantity: 100 ug
• Storage Requirements: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: This antibody is specific to BAD.

For Research Use Only