BAG4 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BAG4.

Supplier:  Abnova Corporation PAB10362

Catalog No. 89-114-808

Description

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. [provided by RefSeq

Specifications

• Antigen: BAG4
• Classification: Polyclonal
• Description: BCL2-associated athanogene 4
• Gene: BAG4
• Gene Symbols: BAG4
• Immunogen: A synthetic peptide corresponding to amino acids 2-16 of human BAG4.
• Regulatory Status: RUO
• Gene ID (Entrez): 9530
• Content And Storage: Store at -20°C. Aliquot to avoid repeated freezing and thawing.

• Applications: Western Blot
• Conjugate: Unconjugated
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: BAG-4, SODD
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only