MilliporeSigma™ Rabbit anti-Bassoon, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABN255

Catalog No. ABN255MI

Description

Specifically detects Bassoon in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting

Protein bassoon (also known as bassoon presynaptic cytomatrix protein, neuronal double zinc finger protein, zinc finger protein 231) is a cytoplasmic protein encoded by the BSN gene in human (also known as KIAA0434 and ZNF23118). Bassoon is found primarily in neurons in brain (PMID 9806829) and most likely functions as a scaffolding protein involved in organizing the presynaptic cytoskeleton. Murine and rodent orthologs are reported to be detected in axon terminals of hippocampal neurons, where it is highly concentrated in the vicinity of the active zone, indicating a potential involvement in cytomatrix organization at the site of neurotransmitter release (PMID 9679147).

Specifications

• Antigen: Bassoon
• Classification: Polyclonal
• Gene Accession No.: O88737
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: Bsn
• Immunogen: GST-tagged recombinant protein corresponding to mouse Bassoon.
• Quantity: 100 μL
• Research Discipline: Neuroscience
• Gene ID (Entrez): NP_031593
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only