BAX (phospho T167), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.

Supplier:  Abnova Corporation PAB29272

Catalog No. 89-130-709

Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq

Specifications

• Antigen: BAX
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: Q07812
• Gene Symbols: BAX
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T167 of human BAX.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: BAX (phospho T167) polyclonal antibody detects endogenous levels of human BAX only when phosphorylated at threonine 167.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunofluorescence
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:100∼1:200) The optimal working dilution should be determined by the end user.
• Gene: BAX
• Gene Alias: BCL2L4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 581
• Target Species: Human
• Form: Liquid

For Research Use Only