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BAX (phospho T167), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89130709 Shop All Abnova Corporation Products
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89-130-709 100 μL
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Catalog No. 89-130-709 Supplier Abnova Corporation Supplier No. PAB29272
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq

Specifications

Antigen BAX
Applications Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.
Dilution Immunofluorescence (1:100∼1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene BAX
Gene Accession No. Q07812
Gene Alias BCL2L4
Gene Symbols BAX
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T167 of human BAX.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 581
Test Specificity BAX (phospho T167) polyclonal antibody detects endogenous levels of human BAX only when phosphorylated at threonine 167.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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