BAX Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BAX.

Supplier:  Abnova Corporation PAB12656

Catalog No. 89-115-989

Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq

Specifications

• Antigen: BAX
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BAX.
• Formulation: In TBS, pH 7.2 (BSA, 10% Proclin300)
• Gene Alias: BCL2L4
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes 23-24 KDa of human BAX derived from A375 cell lysate by Western blot.
• Content And Storage: Store at 4°C. For long term storage store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Upon initial thawing apportion into working aliquots and store at -80°C for up to six months.

• Applications: ELISA, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (1:200) The optimal working dilution should be determined by the end user.
• Gene: BAX
• Gene Symbols: BAX
• Immunogen: A synthetic peptide corresponding to N-terminus of human BAX.
• Regulatory Status: RUO
• Gene ID (Entrez): 581
• Target Species: Human
• Form: Liquid

For Research Use Only