BAX Rabbit anti-Human, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of BAX.
Manufacturer: Abnova Corporation PAB12927
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
|Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to N-terminus 16 amino acids of human BAX.|
|Immunocytochemistry, Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of BAX.|
|In PBS (0.02% sodium azide)|
|Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
For Research Use Only